Selected recent publications:
High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity. K Mattioli, PJ Volders, C Gerhardinger, JC Lee, PG Maass, M Melé*, JLRinn*. Genome research, 2019. * contributed equally
Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs. M Melé, K Mattioli, W Mallard, DM Shechner, C Gerhardinger, JL Rinn. Genome Research, 2017.
“Cat’s Cradling” the 3D genome by the act of lncRNA transcription. M Melé and JL Rinn. Molecular cell, 2016.
The human transcriptome across tissues and individuals. Mele M*, Ferreira PG*, Reverter F*, DeLuca DS, et al. Science, 2015. * contributed equally
Spatiotemporal allele organization by allele-specific CRISPR live-cell imaging (SNP-CLING). PG Maass, AR Barutcu, DM Shechner, CL Weiner, M Melé, JL Rinn. Nature structural & molecular biology, 2018
In vivo Ebola virus infection leads to a strong innate response in circulating immune cells. IS Caballero, AN Honko, SK Gire, SM Winnicki, M Melé, et al, BMC genomics, 2016.
Functional implications of human-specific changes in great ape microRNAs. A Gallego*, M Melé*, I Balcells*, et al. PloS one, 2015. * contributed equally
Multi-tissue analysis of gene regulation in a human population sample: the Genotype-Tissue Expression (GTEx) pilot study. The GTEx Consortium. Science, 2015.
The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild. Prado-Martinez J, Hernando-Herraez I, Lorente-Galdos B et al. BMC Genomics. 2013.
Great ape genetic diversity and population history. Prado-Martinez J, Sudmant PH, Kidd JM et al. Nature. 2013.
The genome of melon (Cucumis melo L.). Garcia-Mas J, Benjak A, Sanseverino W, et al. Proc Natl Acad Sci U S A. 2012.
Recombination networks as genetic markers in a human variation study of the Old World. Javed A,* Melé M*, Pybus M, et al. Hum Genet. 2012. * contributed equally
Recombination gives a new insight in the effective population size and the history of the old world human populations. Melé M, Javed A, Pybus M, et al. Mol Biol Evol. 2012.
IRiS: construction of ARG networks at genomic scales. Javed A, Pybus M, Melé M, Utro F, Bertranpetit J, Calafell F, Parida L. Bioinformatics. 2011.
A new method to reconstruct recombination events at a genomic scale. Melé M, Javed A, Pybus M, Calafell F, Parida L, Bertranpetit J; Genographic Consortium Members. PLoS Comput Biol. 2010.
Similarity in recombination rate estimates highly correlates with genetic differentiation in humans. Laayouni H, Montanucci L, Sikora M, Melé M, et al. PLoS One. 2011.
Minimizing recombinations in consensus networks for phylogeographic studies. Parida L, Javed A, Melé M, Calafell F, Bertranpetit J; Genographic Consortium. BMC Bioinformatics. 2009.
Estimating the ancestral recombinations graph (ARG) as compatible networks of SNP patterns. Parida L, Melé M, Calafell F, Bertranpetit J, Genographic Consortium. J Comput Biol. 2008.
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